Left ventricular thrombus enhancement following intravenous echogenic immunoliposome injection

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Left ventricular thrombus enhancement after intravenous injection of echogenic immunoliposomes: studies in a new experimental model.

BACKGROUND Targeted echogenic immunoliposomes (ELIPs) for ultrasound enhancement of atheroma components have been developed. To date, ELIP delivery has been intra-arterial. To determine whether ELIPs can be given intravenously with enhancement of systemic structures, a left ventricular thrombus (LVT) model was developed. METHODS AND RESULTS In 6 animals plus 1 dose-ranging animal, the apical ...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2002

ISSN: 0735-1097

DOI: 10.1016/s0735-1097(02)81651-5